Current Analysis in
Oncology

Short Communication  |  Published 21 February 2019

Experience with the Advanced HER2 Positive Breast Cancer Treatment in the Motol University Hospital in the Czech Republic

Petra Pokorná* and Jana Prausová

Department of Oncology, University Hospital in Motol, Charles University, V Uvalu 84, 150 00, Prague, Czech Republic

Abstract

In recent years a significant progress is evident in the breast cancer treatment, which leads to the improvement of patients’ prognosis and to the prolongation of their overall survival. There are two new drugs, namely pertuzumab (in combination with trastuzumab and chemotherapy) and trastuzumab emtansine (TDM-1) a conjugate antibody and antineoplastic agent –which can be used in aselect group of patients with metastatic HER2 positive breast cancer. Experience gained from our clinical practice has confirmed both the safety of both chemicals and the gained profit for patients.

Keywords:
Advanced HER2 positive breast tumor, pertuzumab, trastuzumab emtansin, side effects

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